1. Minnesota Vikings (6-0) @ Pittsburgh Steelers (4-2)
Safety Troy Polamalu shook off the rust last week as he returned from a knee injury that he suffered in week one. Wide receiver Percy Harvin is questionable with a shoulder injury and Cornerback Antoine Winfield is doubtful with a right foot injury.
This is a dangerous game for the undefeated Vikings as the defending Super Bowl champions return to elite form.
Prediction: Minnesota 18 - Pittsburgh 24
2.New Orleans Saints (5-0) @ Miami Dolphins (2-3)
The key to this game will be New Orleans' passing game against Miami's secondary - the winner of that match-up will likely determine the outcome. The Dolphins young secondary could take blame for the home opener loss to the Colts. With 5 games under their belt, they have had time to get accustomed to the speed of the game. Watch the match-up between TE Jeremy Shockey and Miami's Linebackers. Tony Gonzalez, Dallas Clark and Antonio Gates gained a total of 317 yards and scored two touchdowns against Miami. Another important element is how well the Dolphins run the ball, including the Wildcat, compared to how effective the Saints stop the rush.
Prediction: New Orleans 27 - Miami 35
3.Arizona Cardinals (3-2) @ New York Giants (5-1)
Although they have struggled, the Cardinals are still a threat to the G-Men with the weapons available on offense; let's not forget the Giants defense allowed seven yards shy of 500 yards last week. It's no secret that Arizona is a pass first, pass often team. An aspect that the Giants defense could concentrate on. A one dimensional will not be enough for the Cardinals to get a win on Sunday. Expect Kurt Warner to have at least two turnovers.
Prediction: Arizona 21 - New York 38